Changes in anterior and posterior hippocampus differentially predict item-space, item-time, and item-item memory improvement.

ABSTRACT: Relational memory improves during middle childhood and adolescence, yet the neural correlates underlying those improvements are debated. Although memory for spatial, temporal, and other associative relations requires the hippocampus, it is not established whether within-individual changes in hippocampal structure contribute to memory improvements from middle childhood into adolescence. Here, we investigated how structural changes in hippocampal head, body, and tail subregions predict improvements in the capacity to remember item-space, item-time, and item-item relations. Memory for each relation and volumes of hippocampal subregions were assessed longitudinally in 171 participants across 3 time points (M_age at T1 = 9.45 years; M_age at T2 = 10.86 years, M_age

SUBMITTER: Lee JK 

PROVIDER: S-EPMC6994624 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature