Effect of paired-pulse stimulus parameters on the two phases of short interval intracortical inhibition in the quadriceps muscle group.

ABSTRACT:

Background

Short interval intracortical inhibition (SICI) is commonly used to assess inhibition in the motor cortex and is known to be affected by the paired-pulse stimulus parameters (i.e., interstimulus interval [ISI], conditioning stimulus intensity [CSI] and test stimulus intensity [TSI]) used during testing. While the effects of stimulus parameters are well-studied in the upper-extremity, evidence in the lower-extremity is lacking.

Objective

To comprehensively examine the effects of alterations in paired-pulse stimulus parameters on the two phases of SICI in the quadriceps muscle group.

Methods

Seventeen adults (8 males, 9 females) volunteered to participate in this study. SICI was examined over a range of CSIs (70-90% active motor threshold [AMT]), TSIs (100-140

SUBMITTER: Krishnan C 

PROVIDER: S-EPMC6995364 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature