Defining the relationship between vaginal and urinary microbiomes.

ABSTRACT:

Background

Although the vaginal and urinary microbiomes have been increasingly well-characterized in health and disease, few have described the relationship between these neighboring environments. Elucidating this relationship has implications for understanding how manipulation of the vaginal microbiome may affect the urinary microbiome and treatment of common urinary conditions.

Objective

To describe the relationship between urinary and vaginal microbiomes using 16S rRNA gene sequencing. We hypothesized that the composition of the urinary and vaginal microbiomes would be significantly associated, with similarities in predominant taxa.

Study design

This multicenter study collected vaginal swabs and catheterized urine samples from 186 women with mixed urinary incontine

SUBMITTER: Komesu YM 

PROVIDER: S-EPMC6995424 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature