Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results.

ABSTRACT:

Background

Preliminary clinical studies on the safety and efficacy of the pipeline embolization device (PED) for the treatment of small/medium aneurysms have demonstrated high occlusion rates with low complications.

Objective

To evaluate the safety and effectiveness of the PED for treatment of wide necked small and medium intracranial aneurysms.

Methods

PREMIER is a prospective, multicenter, single arm trial. Patients were treated with the PED for unruptured wide necked aneurysms, measuring ≤12 mm along the internal carotid artery or vertebral artery, between July 2014 and November 2015. At 1 year post-procedure, the primary effectiveness endpoint was complete occlusion (Raymond grade 1) without major parent vessel stenosis (≤50%) or retreatment, and the primary safet

SUBMITTER: Hanel RA 

PROVIDER: S-EPMC6996098 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature