The application of exercise stress cardiovascular magnetic resonance in patients with suspected dilated cardiomyopathy.

ABSTRACT: OBJECTIVES:The imaging features of dilated cardiomyopathy (DCM) overlap with physiological exercise-induced cardiac remodeling in active and otherwise healthy individuals. Distinguishing the two conditions is challenging. This study examined the diagnostic and prognostic roles of exercise stress imaging in asymptomatic patients with suspected DCM. METHODS:Exercise stress cardiovascular magnetic resonance (CMR) was performed in 60 asymptomatic patients with suspected DCM (dilated left ventricle and/or impaired systolic function on CMR), who also underwent DNA sequencing for DCM-causing genetic variants. Confirmed DCM was defined as genotype- and phenotype-positive (G+P+). Another 100 healthy subjects were recruited to establish normal exercise capacities (peak exercise cardiac index; PeakCI

SUBMITTER: Le TT 

PROVIDER: S-EPMC6996168 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature