Gut microbiota changes in children with autism spectrum disorder: a systematic review.

ABSTRACT:

Background

As more animal studies start to disentangle pathways linking the gut microbial ecosystem and neurobehavioral traits, human studies have grown rapidly. Many have since investigated the bidirectional communication between the gastrointestinal tract and the central nervous system, specifically on the effects of microbial composition on the brain and development.

Methods

Our review at the initial stage aimed to evaluate literature on gut microbial alterations in pediatric neurobehavioral conditions. We searched five literature databases (Embase, PubMed, PsychInfo, Scopus, and Medline) and found 4489 published work. As the mechanisms linking gut microbiota to these conditions are divergent, the scope of this review was narrowed to focus on describing gut dysbiosis in c

SUBMITTER: Ho LKH 

PROVIDER: S-EPMC6996179 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature