Enterotype Bacteroides Is Associated with a High Risk in Patients with Diabetes: A Pilot Study.

ABSTRACT:

Background

More and more studies focus on the relationship between the gastrointestinal microbiome and type 2 diabetes, but few of them have actually explored the relationship between enterotypes and type 2 diabetes. Materials and Methods. We enrolled 134 patients with type 2 diabetes and 37 nondiabetic controls. The anthropometric and clinical indices of each subject were measured. Fecal samples of each subject were also collected and were processed for 16S rDNA sequencing. Multiple logistic regression analysis was used to determine the associations of enterotypes with type 2 diabetes. Multiple linear regression analysis was used to explore the relationship between lipopolysaccharide levels and insulin sensitivity after adjusting for age, BMI, TG, HDL-C, DAO, and TNF-α</

SUBMITTER: Wang J 

PROVIDER: S-EPMC6996672 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature