Extreme obesity does not predict poor cancer outcomes after surgery for renal cell cancer.

ABSTRACT:

Objective

To assess whether extreme obesity (body mass index [BMI] ≥ 40 kg/m(2) ) is associated with peri-operative outcomes, overall survival (OS), cancer-specific survival (CSS), or recurrence-free survival (RFS) after surgical treatment for renal cell carcinoma (RCC).

Patients and methods

After institutional review board approval, we used an institutional database to identify patients treated surgically between January 2000 and December 2014 with a pathological diagnosis of RCC. Comprehensive clinical and pathological data were reviewed. Kaplan-Meier analyses were used to estimate OS, RFS and CSS. Univariate and multivariate Cox proportional hazards analysis was used to evaluate associations with OS, CSS and RFS in patients with extreme obesity, among other known predicti

SUBMITTER: Blute ML 

PROVIDER: S-EPMC6996861 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature