The role of the gut microbiome in the association between habitual anthocyanin intake and visceral abdominal fat in population-level analysis.

ABSTRACT: BACKGROUND:Flavonoid intake modifies the composition of the gut microbiome, which contributes to the metabolism of flavonoids. Few studies have examined the contribution of the gut microbiome to the health benefits associated with flavonoid intake. OBJECTIVES:We aimed to examine associations between habitual intakes of flavonoid subclasses and MRI-determined visceral (VAT) and subcutaneous (SAT) adipose tissue. Uniquely, we also identified associations between the aforementioned measurements and gut microbiome composition sequenced from 16S ribosomal RNA genes. METHODS:We undertook cross-sectional analyses of 618 men and women (n = 368 male), aged 25-83 y, from the PopGen cohort. RESULTS:Higher intake of anthocyanins was associated with lower amounts of VAT [tertile (T)3-T1:  -0.49 dm3; β:

SUBMITTER: Jennings A 

PROVIDER: S-EPMC6997102 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature