Best (but oft-forgotten) practices: identifying and accounting for regression to the mean in nutrition and obesity research.

ABSTRACT:

Background

Regression to the mean (RTM) is a statistical phenomenon where initial measurements of a variable in a nonrandom sample at the extreme ends of a distribution tend to be closer to the mean upon a second measurement. Unfortunately, failing to account for the effects of RTM can lead to incorrect conclusions on the observed mean difference between the 2 repeated measurements in a nonrandom sample that is preferentially selected for deviating from the population mean of the measured variable in a particular direction. Study designs that are susceptible to misattributing RTM as intervention effects have been prevalent in nutrition and obesity research. This field often conducts secondary analyses of existing intervention data or evaluates intervention effects in those most at

SUBMITTER: Thomas DM 

PROVIDER: S-EPMC6997628 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature