Genetic characterization of HIV-1 epidemic in Anhui Province, China.

ABSTRACT:

Background

Anhui Province in China is facing a severe HIV epidemic with an increasing number of newly diagnosed cases.

Methods

In this study, HIV genetic characteristics in the province were investigated. Newly reported HIV-positive individuals from 15 districts of Anhui Province were enrolled and interviewed. Total viral RNA was extracted from plasma isolated from blood samples. We amplified and sequenced an HIV pol fragment of the 1062 bp. The sequences were used for determination of HIV subtypes and the presence of drug resistance mutations. Transmission networks were constructed to explore possible relationships. And all of assembled partial pol genes were submitted to the Stanford HIV Drug Resistance Database website to find the transmitted drug resistance.

Results</

SUBMITTER: Zhang D 

PROVIDER: S-EPMC6998069 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature