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Development, diagnosis and therapy of ketosis in non-gravid and non-lactating Guinea pigs.


ABSTRACT: BACKGROUND:Ketosis is a metabolic disorder often triggered by anorexia in animals fed on high energy diets. Although mostly described in pregnant female guinea pigs, under the name of pregnancy toxicosis; there is limited information on ketosis in males and non-pregnant females, often presented to clinics with anorexia or inappetence. The objective of this study was to observe progression of ketosis in guinea pigs, document the changes and evaluate diagnostic methods and a therapeutic approach. RESULTS:Twenty eight adult guinea pigs (Cavia porcellus), castrated males and intact females of obese and slim body condition were fasted for 3 days and refed afterwards. The slim animals served as control group for body condition. Either slim and fat animals were divided into two treatment groups:

SUBMITTER: Schmid NS 

PROVIDER: S-EPMC6998326 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature