Polymersomes for biotechnological applications: Large-scale production of nano-scale vesicles.

ABSTRACT: Polymersomes have some fundamental advantages compared to their liposomal counterparts. Due to the increased stability of the polymeric membrane, polymersomes are intended to be reasonably applicable as carrier-systems and universal reaction compartments for diverse medical and biotechnological applications. Regardless of the application area, suitable methods to produce large vesicle quantities in a controlled and cost-effective manner have to be developed to put polymersome technology into action at the industrial scale. In this work, the amphiphilic triblock copolymer poly(2-methyloxazoline)15-poly(dimethylsiloxane)68-poly(2-methyloxazoline)15 was formed into uniform polymersomes. A recently established production process, based on the use of miniaturized stirred-tank reactors at the mi

SUBMITTER: Poschenrieder ST 

PROVIDER: S-EPMC6999365 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature