Prenatal and childhood predictors of hair cortisol concentration in mid-childhood and early adolescence.

ABSTRACT:

Background

Hair cortisol concentration (HCC) is an increasingly used measure of systemic cortisol concentration. However, determinants of HCC in children and adolescents are unclear because few prospective studies have been conducted to date.

Study design

We followed 725 children in Project Viva, a pre-birth cohort study of mothers and children, who provided hair samples at mid-childhood (median age: 7.7 years) or early adolescence (median age: 12.9 years). We examined associations of various factors measured from pregnancy to mid-childhood with HCC in mid-childhood and early adolescence, as well as change in HCC between these time points (ΔHCC).

Results

There were 426 children with HCC measurements in both mid-childhood and early adolescence, 173 children with measur

SUBMITTER: Petimar J 

PROVIDER: S-EPMC6999889 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature