Psychiatric genomics researchers' perspectives on best practices for returning results to individual participants.

ABSTRACT:

Purpose

Large-scale array-based and sequencing studies have advanced our understanding of the genetic architecture of psychiatric disorders, but also increased the potential to generate an exponentially larger amount of clinically relevant findings. As genomic testing becomes more widespread in psychiatry research, urgency grows to establish best practices for offering return of results (RoR) to individuals at risk or diagnosed with a psychiatric disorder.

Methods

We interviewed an international sample (n = 39) of psychiatric genetics researchers to examine conceptualizations of "best practices" for RoR to individual research participants.

Results

While the vast majority of researchers do not offer RoR, most believed medically actionable findings (85%) and clinically

SUBMITTER: Kostick K 

PROVIDER: S-EPMC7000323 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature