Creating genetic reports that are understood by nonspecialists: a case study.

ABSTRACT:

Purpose

Guidelines recommend that genetic reports should be clear to nonspecialists, including patients. We investigated the feasibility of creating reports for cystic fibrosis carrier testing through a rapid user-centered design process that built on a previously developed generic template. We evaluated the new reports' communication efficacy and effects on comprehension against comparable reports used in current clinical practice.

Methods

Thirty participants took part in three rounds of interviews. Usability problems were identified and rectified in each round. One hundred ninety-three participants took part in an evaluation of the resulting reports measuring subjective comprehension, risk probability comprehension, perceived communication efficacy, and other factors, as c

SUBMITTER: Recchia G 

PROVIDER: S-EPMC7000324 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature