Disrupted Brain Structural Connectivity Network in Subcortical Ischemic Vascular Cognitive Impairment With No Dementia.

ABSTRACT: The alteration of the functional topological organization in subcortical ischemic vascular cognitive impairment with no dementia (SIVCIND) patients has been illuminated by previous neuroimaging studies. However, in regard to the changes in the structural connectivity of brain networks, little has been reported. In this study, a total of 27 subjects, consisting of 13 SIVCIND patients, and 14 normal controls, were recruited. Each of the structural connectivity networks was constructed by diffusion tensor tractography. Subsequently, graph theory, and network-based statistics (NBS) were employed to analyze the whole-brain mean factional anisotropy matrix. After removing the factor of age, gender, and duration of formal education, the clustering coefficients (C p ) and global efficiency (E glob

SUBMITTER: Sang L 

PROVIDER: S-EPMC7000429 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature