Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study.

ABSTRACT:

Background

The combination of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 (commercially available as Probi Defendum^®) has previously been reported to reduce the incidence, duration and severity of naturally acquired common colds in adults. The aim of the present study was to evaluate the impact of Probi Defendum^® on aspects of common cold in healthy children 1-6 years of age attending day care.

Methods

A total of 131 children, out of the planned 320, were recruited into the study during 1 common cold season and randomised to consume once daily either 10⁹ CFU (colony forming units) of the probiotic product or placebo. Due to unforeseen reasons, the recruitment of more children did not continue beyond the first cold season.

SUBMITTER: Lazou Ahren I 

PROVIDER: S-EPMC7000506 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature