Triple therapy for COPD: a crude analysis from a systematic review of the evidence.

ABSTRACT: We systematically reviewed the current knowledge on fixed-dose triple therapies for the treatment of chronic obstructive pulmonary disease (COPD), with a specific focus on its efficacy versus single bronchodilation, double fixed dose combinations, and open triple therapies. Articles were retrieved from PubMed, Embase, and Scopus up to 3 August 2018. We selected articles with randomized controlled or crossover design conducted in patients with COPD and published as full-length articles or scientific letters, evaluating triple therapy combinations in a single or different inhaler, and with efficacy data versus monocomponents, double combinations, or open triple therapies. Our systematic search reported 108 articles, of which 24 trials were finally selected for the analysis. A t

SUBMITTER: Lopez-Campos JL 

PROVIDER: S-EPMC7000908 | biostudies-literature | 2019 Jan-Dec

REPOSITORIES: biostudies-literature