Primary Angle Closure Glaucoma-associated Genetic Polymorphisms in Northeast Iran.

ABSTRACT:

Purpose

To evaluate the association of five different polymorphisms from a genome-wide-associated study with susceptibility to glaucoma in the northeast Iranian population.

Methods

Hundred and thirty patients with primary angle closure glaucoma (PACG) and 130 healthy controls were genotyped for the polymorphic regions with the aid of tetra-amplification refractory mutation system-polymerase chain reaction. The association of these variants with the disease susceptibility was measured statistically with the logistic regression method.

Results

Hundred and thirty patients with PACG (53 males, 77 females) with a mean age of 64.5 ± 6.2 years and 130 healthy control subjects (51 males, 79 females) with a mean age of 64.0 ± 5.7 years were selected for evaluation. There was a

SUBMITTER: Yousefian A 

PROVIDER: S-EPMC7001019 | biostudies-literature | 2020 Jan-Mar

REPOSITORIES: biostudies-literature