Preventing early childhood caries with silver diamine fluoride: study protocol for a randomised clinical trial.

ABSTRACT:

Background

Silver diamine fluoride (SDF) solution is effective in arresting early childhood caries (ECC). Previous studies have suggested that it might exert a preventive effect in managing ECC. However, no well-designed clinical trials have yet been performed to study the effect of SDF on caries prevention. The objective of this randomised clinical trial is to determine whether 38% SDF solution is superior to 5% sodium fluoride (NaF) varnish in preventing new carious lesions in primary anterior teeth.

Methods/design

This is a phase II, single-centre, randomised, double-blind, active-controlled, parallel-group pragmatic trial. The hypothesis tested is that 38% SDF would be more effective than 5% NaF in preventing new caries development in primary anterior teeth. Approximatel

SUBMITTER: Gao SS 

PROVIDER: S-EPMC7001262 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature