Association between suicide death and concordance with benzodiazepine treatment guidelines for anxiety and sleep disorders.

ABSTRACT:

Objective

Guidelines for management of anxiety and sleep disorders emphasize antidepressant medications and/or psychotherapy as first/second-line and benzodiazepines as third-line treatments. We evaluated the association between suicide death and concordance with benzodiazepine guidelines.

Methods

Retrospective case-control study of patients with anxiety and/or sleep disorders from health systems across 8 U.S. states within the Mental Health Research Network. Suicide death cases were matched to controls on year and health system. Appropriate benzodiazepine prescribing defined as: no monotherapy, no long duration, and/or age < 65 years. The association between guideline concordance and suicide death was evaluated, adjusting for diagnostic and treatment covariates.

Results<

SUBMITTER: Boggs JM 

PROVIDER: S-EPMC7001528 | biostudies-literature | 2020 Jan - Feb

REPOSITORIES: biostudies-literature