Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes.

ABSTRACT: Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic disease transmission and control in low- and middle-income countries. Rabies is an almost invariably fatal viral disease that causes a large public health and economic burden in Asia and Africa, despite being entirely vaccine preventable. With policy efforts now directed towards achieving a global goal of zero dog-mediated human rabies deaths by 2030, establishing effective surveillance tools is critical. Genomic data can provide important and unique insights into rabies spread and persistence that can direct control efforts. However, capacity for genomic research in low- and middle-income countries is held back by limited laboratory infrastructure, cost, suppl

SUBMITTER: Brunker K 

PROVIDER: S-EPMC7001756 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature