Francisella novicida and F. philomiragia biofilm features conditionning fitness in spring water and in presence of antibiotics.

ABSTRACT: Biofilms are currently considered as a predominant lifestyle of many bacteria in nature. While they promote survival of microbes, biofilms also potentially increase the threats to animal and public health in case of pathogenic species. They not only facilitate bacteria transmission and persistence, but also promote spreading of antibiotic resistance leading to chronic infections. In the case of Francisella tularensis, the causative agent of tularemia, biofilms have remained largely enigmatic. Here, applying live and static confocal microscopy, we report growth and ultrastructural organization of the biofilms formed in vitro by these microorganisms over the early transition from coccobacillary into coccoid shape during biofilm assembly. Using selective dispersing agents, we provided evidenc

SUBMITTER: Siebert C 

PROVIDER: S-EPMC7001994 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature