Predictors of Hip Fracture Despite Treatment with Bisphosphonates among Frail Older Adults.

ABSTRACT:

Objectives

Bisphosphonates are effective at preventing hip fractures among older adults, yet many patients still fracture while on treatment and may benefit from additional preventive interventions. Little data are specifically available to target such efforts among bisphosphonate users. We aimed to identify predictors of hip fracture unique to frail older adults initiating pharmacologic treatment for osteoporosis.

Design

Retrospective cohort using 2008-2013 linked national Minimum Data Set assessments, Medicare claims, and nursing home (NH) facility data.

Setting

NHs in the United States.

Participants

Long-stay NH residents 65 years or older who initiated treatment with a bisphosphonate (N = 17 753). Estimates for bisphosphonate initiators were contrasted with

SUBMITTER: Zullo AR 

PROVIDER: S-EPMC7002229 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature