Management of primary pterygium with intra-lesional injection of 5 flurouracil and bevacizumab (Avastin).

ABSTRACT:

Background

To assess the efficacy of combined 5FU and Avastin injections in the treatment of primary pterygium METHODS: Sixteen eyes with primary pterygium received intralesional 5 fluorouracil and Avastin (2.5-5 mg) injections every 2 weeks for a maximum of five injections. Fourteen eyes of 14 patients received five injections, one eye received three injections and one eye received two injections. All eyes were followed at monthly intervals for 3 months after last injection. Tissue was obtained by surgical excision of primary pterygium from four eyes who received injections and three eyes with primary pterygium who did not receive injections (control) and subjected to immunohistological examination for beta fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF)

SUBMITTER: Ghoz N 

PROVIDER: S-EPMC7002451 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature