New markers for regulation of transcription and macromolecule metabolic process in porcine oocytes during in vitro maturation.

ABSTRACT: Oocyte maturation is essential for proper fertilization, embryo implantation and early development. While the physiological conditions of these processes are relatively well‑known, its exact molecular mechanisms remain widely undiscovered. Oocyte growth, differentiation and maturation are therefore the subject of scientific debate. Precious literature has indicated that the oocyte itself serves a regulatory role in the mechanisms underlying these processes. Hence, the present study performed expression microarrays to analyze the complete transcriptome of porcine oocytes during their in vitro maturation (IVM). Pig material was used for experimentation, as it possesses similarities to the reproductive processes and general genetic proximities of Sus scrofa to human. Oocytes, isolated from th

SUBMITTER: Brazert M 

PROVIDER: S-EPMC7002967 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature