Improving symptom burden in adults with persistent post-concussive symptoms: a randomized aerobic exercise trial protocol.

ABSTRACT:

Background

Persistent post-concussive symptoms (PPCS) affect up to 30% of individuals following mild traumatic brain injury. PPCS frequently includes exercise intolerance. Sub-symptom threshold aerobic exercise has been proposed as a treatment option for symptom burden and exercise intolerance in this population. The primary aim of this study is to evaluate whether a progressive, sub-symptom threshold aerobic exercise program can alleviate symptom burden in adults with PPCS.

Methods

Fifty-six adults (18-65) with PPCS (>3mos-5 yrs) will be randomized into two groups: an immediate start 12-week aerobic exercise protocol (AEP) or delayed start 6-week placebo-like stretching protocol (SP), followed by AEP. Aerobic or stretching activities will be completed 5x/week for 30 mins du

SUBMITTER: Mercier LJ 

PROVIDER: S-EPMC7003424 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature