A systematic review of methodology used in the development of prediction models for future asthma exacerbation.

ABSTRACT:

Background

Clinical prediction models are widely used to guide medical advice and therapeutic interventions. Asthma is one of the most common chronic diseases globally and is characterised by acute deteriorations. These exacerbations are largely preventable, so there is interest in using clinical prediction models in this area. The objective of this review was to identify studies which have developed such models, determine whether consistent and appropriate methodology was used and whether statistically reliable prognostic models exist.

Methods

We searched online databases MEDLINE (1948 onwards), CINAHL Plus (1937 onwards), The Cochrane Library, Web of Science (1898 onwards) and ClinicalTrials.gov, using index terms relating to asthma and prognosis. Data was extracted and as

SUBMITTER: Bridge J 

PROVIDER: S-EPMC7003428 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature