The cardiovascular risk profile of middle-aged women with polycystic ovary syndrome.

ABSTRACT:

Objectives

Contradictory results have been reported regarding the association between polycystic ovary syndrome (PCOS) and cardiovascular disease (CVD). We assessed the cardiometabolic phenotype and prevalence of CVD in middle-aged women with PCOS, compared with age-matched controls from the general population, and estimated 10-year CVD risk and cardiovascular health score.

Design

A cross-sectional study.

Participants

200 women aged >45 with PCOS, and 200 age-matched controls.

Measurements

Anthropometrics, insulin, lipid levels, prevalence of metabolic syndrome and type II diabetes. Ten-year Framingham risk score and the cardiovascular health score were calculated, and carotid intima-media thickness (cIMT) was measured.

Results

Mean age was 50.5 years (S

SUBMITTER: Meun C 

PROVIDER: S-EPMC7003818 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature