Greater genetic and regulatory plasticity of retained duplicates in Epichloe endophytic fungi.

ABSTRACT: Gene duplicates can act as a source of genetic material from which new functions arise. Most duplicated genes revert to single copy genes and only a small proportion are retained. However, it remains unclear why some duplicate genes persist in the genome for an extended time. We investigate this question by analysing retained gene duplicates in the fungal genus Epichloë, ascomycete fungi that form close endophytic symbioses with their host grasses. Retained duplicates within this genus have two independent origins, but both long pre-date the origin and diversification of the genus Epichloë. We find that loss of retained duplicates within the genus is frequent and often associated with speciation. Retained duplicates have faster evolutionary rates (Ka) and show relaxed selection (Ka/Ks) com

SUBMITTER: Wu B 

PROVIDER: S-EPMC7004115 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature