Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis.

ABSTRACT: Sexual dimorphism requires regulation of gene expression in developing organisms. These developmental differences are caused by differential expression of genes and isoforms. The effect of expressing a gene is also influenced by which other genes are simultaneously expressed (functional interactions). However, few studies have described how these processes change across development. We compare the dynamics of differential expression, isoform switching and functional interactions in the sexual development of the model parasitoid wasp Nasonia vitripennis, a system that permits genome wide analysis of sex bias from early embryos to adults. We find relatively little sex-bias in embryos and larvae at the gene level, but several sub-networks show sex-biased functional interactions in early devel

SUBMITTER: Rago A 

PROVIDER: S-EPMC7004391 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature