A comparison between the TEG 6s and TEG 5000 analyzers to assess coagulation in trauma patients.

ABSTRACT:

Background

Trauma-induced coagulopathy is a major driver of mortality following severe injury. Viscoelastic goal-directed resuscitation can reduce mortality after injury. The TEG 5000 system is widely used for viscoelastic testing. However, the TEG 6s system incorporates newer technology, with encouraging results in cardiovascular interventions. The purpose of this study was to validate the TEG 6s system for use in trauma patients.

Methods

Multicenter noninvasive observational study for method comparison conducted at 12 US Levels I and II trauma centers. Agreement between the TEG 6s and TEG 5000 systems was examined using citrated kaolin reaction time (CK.R), citrated functional fibrinogen maximum amplitude (CFF.MA), citrated kaolin percent clot lysis at 30 minutes (CK.LY30)

SUBMITTER: Neal MD 

PROVIDER: S-EPMC7004476 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature