Numerical Analysis of Airway Mucus Clearance Effectiveness Using Assisted Coughing Techniques.

ABSTRACT: Cough is a protective respiratory reflex used to clear respiratory airway mucus. For patients with cough weakness, such as chronic obstructive pulmonary disease, neuromuscular weakness disease and other respiratory diseases, assisted coughing techniques are essential to help them clear mucus. In this study, the Eulerian wall film model was applied to simulate the coughing clearance process through a computational fluid dynamics methodology. Airway generation 0 to generation 2 based on realistic geometry is considered in this study. To quantify cough effectiveness, cough efficiency was calculated. Moreover, simulations of four different coughing techniques applied for chronic obstructive pulmonary disease and neuromuscular weakness disease were conducted. The influences of mucus film thickn

SUBMITTER: Ren S 

PROVIDER: S-EPMC7005022 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature