Cancer-Related Stroke: An Emerging Subtype of Ischemic Stroke with Unique Pathomechanisms.

ABSTRACT: Systemic cancer and ischemic stroke are common conditions and two of the most frequent causes of death among the elderly. The association between cancer and stroke has been reported worldwide. Stroke causes severe disability for cancer patients, while cancer increases the risk of stroke. Moreover, cancer-related stroke is expected to increase due to advances in cancer treatment and an aging population worldwide. Because cancer and stroke share risk factors (such as smoking and obesity) and treatment of cancer can increase the risk of stroke (e.g., accelerated atherosclerosis after radiation therapy), cancer may accelerate conventional stroke mechanisms (i.e., atherosclerosis, small vessel disease, and cardiac thrombus). In addition, active cancer and chemotherapy may enhance thrombin gener

SUBMITTER: Bang OY 

PROVIDER: S-EPMC7005348 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature