Opto-acoustic imaging of relative blood oxygen saturation and total hemoglobin for breast cancer diagnosis.

ABSTRACT: Opto-acoustic imaging involves using light to produce sound waves for visualizing blood in biological tissue. By using multiple optical wavelengths, diagnostic images of blood oxygen saturation and total hemoglobin are generated using endogenous optical contrast, without injection of any external contrast agent and without using any ionizing radiation. The technology has been used in recent clinical studies for diagnosis of breast cancer to help distinguish benign from malignant lesions, potentially reducing the need for biopsy through improved diagnostic imaging accuracy. To enable this application, techniques for mapping oxygen saturation differences within tissue are necessary. Using biologically relevant opto-acoustic phantoms, we analyze the ability of an opto-acoustic imaging system

SUBMITTER: Zalev J 

PROVIDER: S-EPMC7005558 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature