Effect of Thyroid Hormones on Kidney Function in Patients after Kidney Transplantation.

ABSTRACT: Elevated levels of thyroid-stimulating-hormone (TSH) are associated with reduced glomerular filtration rate (GFR) and increased risk of developing chronic kidney disease even in euthyroid patients. Thyroid hormone replacement therapy has been shown to delay progression to end-stage renal disease in sub-clinically hypothyroid patients with renal insufficiency. However, such associations after kidney transplantation were never investigated. In this study the association of thyroid hormones and estimated GFR (eGFR) in euthyroid patients after kidney transplantation was analyzed. In total 398 kidney transplant recipients were assessed retrospectively and association between thyroid and kidney function parameters at and between defined time points, 12 and 24 months after transplantation, was st

SUBMITTER: Schairer B 

PROVIDER: S-EPMC7005730 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature