Plasma lipid profile associates with the improvement of psychological well-being in individuals with perceived stress symptoms.

ABSTRACT: Psychological stress is a suggested risk factor of metabolic disorders, but molecular mediators are not well understood. We investigated the association between the metabolic profiles of fasting plasma and the improvement of psychological well-being using non-targeted liquid chromatography-mass spectrometry (LC-MS) platform. The metabolic profiles of volunteers participating in the face-to-face intervention group (n = 60) in a randomised lifestyle intervention were compared to ones of controls (n = 64) between baseline and 36-week follow-up. Despite modest differences in metabolic profile between groups, we found associations between phosphatidylcholines (PCs) and several parameters indicating stress, adiposity, relaxation, and recovery. The relief of heart-rate-variability-based stress ha

SUBMITTER: Noerman S 

PROVIDER: S-EPMC7005736 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature