Interference of oleamide with analytical and bioassay results.

ABSTRACT: During sample preparation and analysis, samples are coming in contact with different labware materials. By four unrelated analytical (phytochemical and pharmaceutical) case-studies and employing different analytical techniques, we demonstrated the potential misinterpretation of analytical results due to the use of contaminants-leaching labware during sample handling. Oleamide, a common polymer lubricant and a bioactive compound, was identified as a main analytical interference, leaching from different labware items into solvents, recognised as chemically compatible with the tested polymer material. Moreover, anti-inflammatory effect of oleamide at 100 μg mL^-1 and considerable pro-inflammatory effect of the plastic syringe extractables (containing oleamide) at the same level were

SUBMITTER: Jug U 

PROVIDER: S-EPMC7005802 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature