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Epistatic regulation of growth in Atlantic salmon revealed: a QTL study performed on the domesticated-wild interface.


ABSTRACT: BACKGROUND:Quantitative traits are typically considered to be under additive genetic control. Although there are indications that non-additive factors have the potential to contribute to trait variation, experimental demonstration remains scarce. Here, we investigated the genetic basis of growth in Atlantic salmon by exploiting the high level of genetic diversity and trait expression among domesticated, hybrid and wild populations. RESULTS:After rearing fish in common-garden experiments under aquaculture conditions, we performed a variance component analysis in four mapping populations totaling ~ 7000 individuals from six wild, two domesticated and three F1 wild/domesticated hybrid strains. Across the four independent datasets, genome-wide significant quantitative trait loci (QTLs) associa

SUBMITTER: Besnier F 

PROVIDER: S-EPMC7006396 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature