A novel transcript of MEF2D promotes myoblast differentiation and its variations associated with growth traits in chicken.

ABSTRACT:

Background

Development of skeletal muscle is closely related to broiler production traits. The myocyte-specific enhancer binding factor (MEF) 2D gene (MEF2D) and its variant transcripts play important parts in myogenesis.

Methods

To identify the transcript variants of chicken MEF2D gene and their function, this study cloned chicken MEF2D gene and identified its transcript variants from different tissue samples. The expression levels of different transcripts of MEF2D gene in different tissues and different periods were measured, and their effects on myoblast proliferation and differentiation were investigated. Variations in MEF2D were identified and association analysis with chicken production traits carried out.

Results

Four novel transcrip

SUBMITTER: Ouyang H 

PROVIDER: S-EPMC7006513 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature