Implementation of Pharmacogenetics in Primary Care: A Multi-Stakeholder Perspective.

ABSTRACT:

Introduction

Aberrant pharmacogenetic variants occur in a high proportion of people and might be relevant for the prescription of over 26 drugs in primary care. Early identification of patients who metabolize these drugs more rapidly or slowly than average could predict therapeutic effectivity and safety. Yet implementation of pharmacogenetics is progressing slowly. A high public health impact can potentially be achieved by increasing the proportion of people tested, when and where eligible according to clinical validity and utility.

Methods

In this study we defined actions, roles, and responsibilities for implementation of pharmacogenetics in primary care in consultation with stakeholder groups, by using a three-step mixed-methods approach. First, to define barriers and fac

SUBMITTER: Rigter T 

PROVIDER: S-EPMC7006602 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature