Association between TSH levels within the reference range and adiposity markers at the baseline of the ELSA-Brasil study.

ABSTRACT: BACKGROUND:The association of thyrotropin (TSH) with overall (body mass index, BMI), visceral (waist circumference and steatosis), and upper subcutaneous (neck circumference, NC) adiposity markers is still controversial, and the aim of this study is to assess these associations in the baseline data of a large cohort from ELSA-Brasil. METHODS AND FINDINGS:This cross-sectional study included 11,224 participants with normal thyroid function (normal TSH levels). BMI, waist circumference, NC and steatosis, defined by hepatic attenuation (mild or moderate/severe) were the explicative variables. TSH levels were log transformed (logTSH), and multivariate linear regression models were generated to estimate the associations between logTSH and BMI (continuous and categorized), waist circumference, NC

SUBMITTER: Diniz MFHS 

PROVIDER: S-EPMC7006933 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature