Anemia and clinical outcomes in patients with non-dialysis dependent or dialysis dependent severe chronic kidney disease: a Danish population-based study.

ABSTRACT:

Background

Routine clinical evidence is limited on clinical outcomes associated with anemia in patients with severe chronic kidney disease (CKD).

Methods

We linked population-based medical databases to identify individuals with severe CKD (eGFR < 30 mL/min/1.73 m²) in Northern Denmark from 2000 to 2016, including prevalent patients as of 1 January 2009 or incident patients hereafter into the study. We classified patients as non-anemic (≥ 12/≥ 13 g/dl hemoglobin (Hgb) in women/men), anemia grade 1 (10-12/13 g/dl Hgb in women/men), 2 (8-10 g/dl Hgb), and 3+ (< 8 g/dl Hgb), allowing persons to contribute with patient profiles and risk time in consecutively more severe anemia grade cohorts. Patients were stratified by dialysis status and followed for clinical outcomes

SUBMITTER: Toft G 

PROVIDER: S-EPMC7007417 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature