Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke.

ABSTRACT: BACKGROUND:It is unclear whether non-high-density lipoprotein cholesterol (Non-HDL-C) is associated with haemorrhagic transformation (HT) after acute ischaemic stroke (AIS). We aimed to explore the association between Non-HDL-C and HT, as well as compare the predictive values of Non-HDL-C and low-density lipoprotein cholesterol (LDL-C) for HT. METHODS:We consecutively enrolled AIS patients within 7 days of stroke onset. Participants were divided into four categories according to quartiles of Non-HDL-C. HT was assessed by follow-up brain imaging. We assessed the association between Non-HDL-C, LDL-C and HT in multivariate logistic regression analysis. RESULTS:A total of 2043 patients were included, among whom 232 were identified as HT. Compared with the highest quartiles, the first, second a

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7007671 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature