Classical galactosemia: neuropsychological and psychosocial functioning beyond intellectual abilities.

ABSTRACT:

Background

Despite early diagnosis and treatment, Classical Galactosemia (CG) patients frequently develop long-term complications, such as cognitive impairment. Available literature primarily reports on general intellectual abilities and shows a substantially lower Full Scale Intelligence Quotient (FSIQ) in CG patients than in the general population. Both problems in social functioning as well as internalizing problems are often reported in CG patients. The combination of intelligence, cognitive functioning, behavior and social functioning has not been studied systematically in CG patients.

Methods

To determine if CG patients demonstrate a specific neuropsychological and psychosocial profile, we investigated intelligence, functioning on multiple cognitive domains, behavior a

SUBMITTER: Welsink-Karssies MM 

PROVIDER: S-EPMC7007688 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature