Automatic EPAP intelligent volume-assured pressure support is effective in patients with chronic respiratory failure: A randomized trial.

ABSTRACT:

Background and objective

Patients with chronic respiratory failure are increasingly managed with domiciliary non-invasive ventilation (NIV). There may be limited ability to provide NIV titration for these complex patients, and ventilatory requirements and upper airway support needs may change over time. Therefore, an automatically adjusting expiratory positive airway pressure (AutoEPAP) algorithm may offer advantages over manually adjusted EPAP for treating these patients. This study compared 4% oxygen desaturation index (ODI4%) values during the use of an AutoEPAP algorithm versus manual EPAP titration with the intelligent volume-assured pressure support (iVAPS) algorithm.

Methods

This prospective, single-blind, randomized, crossover study was conducted at six US sites. Pat

SUBMITTER: Orr JE 

PROVIDER: S-EPMC7007762 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature