The Possible Impact of Aortic Stiffness on Quality of Late Life: An Exploratory Study.

ABSTRACT:

Purpose

Aortic stiffness (AS) is associated with cardiovascular events and all-cause mortality in the older population. AS might also influence the health-related quality of life (HRQOL) as a result of the negative effects of AS on cognitive and physical morbidity. We aimed to investigate the possible association between AS and HRQOL in people aged 75 years and over.

Patients and methods

This cross-sectional study was part of the SCOPE study, an international multicenter cohort observational study. The indicators for AS were aortic pulse wave velocity (aPWV) and central pulse pressure (cPP). HRQOL was assessed using the EQ-5D index and the EQ-5D visual analog scale (VAS). ANCOVA and multivariate regression models were used to investigate possible associations.

Results

SUBMITTER: Tap L 

PROVIDER: S-EPMC7007799 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature