Ultraviolet Radiation Exposure and the Risk of Herpes Zoster in Three Prospective Cohort Studies.

ABSTRACT:

Objective

To examine the association between ultraviolet radiation (UVR) exposure and the risk of herpes zoster (HZ) in 3 prospective cohorts.

Patients and methods

We included 205,756 participants from the Health Professionals Follow-up Study (HPFS; 1986-2008), Nurses' Health Study (NHS; 1996-2012), and Nurses' Health Study II (NHS II; 1991-2013). Ambient UVR exposure was based on updated geocoded address histories linked with a high-resolution spatiotemporal ultraviolet model. Incident HZ cases were identified by self-reported clinician diagnosis. Sunburn history and medical, lifestyle, and dietary factors were assessed using biennial questionnaires. Multivariable Cox proportional hazards models were used.

Results

A total of 24,201 cases of HZ occurred during 3,626,1

SUBMITTER: Kawai K 

PROVIDER: S-EPMC7007833 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature