MR-based cardiac and respiratory motion correction of PET: application to static and dynamic cardiac ¹⁸F-FDG imaging.

ABSTRACT: Motion of the myocardium deteriorates the quality and quantitative accuracy of cardiac PET images. We present a method for MR-based cardiac and respiratory motion correction of cardiac PET data and evaluate its impact on estimation of activity and kinetic parameters in human subjects. Three healthy subjects underwent simultaneous dynamic ¹⁸F-FDG PET and MRI on a hybrid PET/MR scanner. A cardiorespiratory motion field was determined for each subject using navigator, tagging and golden-angle radial MR acquisitions. Acquired coincidence events were binned into cardiac and respiratory phases using electrocardiogram and list mode-driven signals, respectively. Dynamic PET images were reconstructed with MR-based motion correction (MC) and without motion correction (NMC). Parametric ima

SUBMITTER: Petibon Y 

PROVIDER: S-EPMC7007962 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature